Comment on: Riazi et al. Can Ultrasound of the Tibial Nerve Detect Diabetic Peripheral Neuropathy? A Cross-Sectional Study. Diabetes Care 2012;35:2575-2579

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Comment on: Riazi et al. Can Ultrasound of the Tibial Nerve Detect Diabetic Peripheral Neuropathy? A Cross-Sectional Study. Diabetes Care 2012;35:2575–2579

R iazi et al. (1) report that ultrasound demonstrates a consistent enlargement of the posterior tibial nerve in the distal leg in diabetes sensorimotor polyneuropathy (DSP). They also describe an inverse relation between calculated cross-sectional area and objectively measured nerve conduction studies and a direct relationship with subjective DSP severity. Their discussion suggests ultrasound u...

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Can Ultrasound of the Tibial Nerve Detect Diabetic Peripheral Neuropathy?

OBJECTIVE Peripheral nerve imaging by portable ultrasound (US) may serve as a noninvasive and lower-cost alternative to nerve conduction studies (NCS) for diagnosis and staging of diabetic sensorimotor polyneuropathy (DSP). We aimed to examine the association between the size of the posterior tibial nerve (PTN) and the presence and severity of DSP. RESEARCH DESIGN AND METHODS We performed a c...

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CanUltrasoundof theTibialNerveDetect Diabetic Peripheral Neuropathy? A cross-sectional study

RESULTSdFifty-five patients had DSP. The mean CSA of the PTN in DSP compared with control subjects at distances of 1 (23.03 vs. 17.72 mm; P = 0.004), 3 (22.59 vs. 17.69 mm; P, 0.0001), and 5 cm (22.05 vs. 17.25 mm; P = 0.0005) proximal to the medial malleolus was significantly larger. Although the area under the curve (AUC) for CSA measurements at all three anatomical levels was similar, the CS...

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Comment on Ferrannini et al. Diabetes Care 2016;39:1108-1114. Comment on Mudaliar et al. Diabetes Care 2016;39:1115-1122.

In their recent articles, Ferrannini et al. (1) and Mudaliar et al. (2) suggest that increased ketonemia, improving heart function, might explain the positive results of the BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME) study. This suggestion perfectly fits with our recently published hypothesis that glucagon could be the key...

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The usefulness of quantifying intraepidermal nerve fibers density in the diagnostic of diabetic peripheral neuropathy: a cross-sectional study.

BACKGROUND Distal symmetric polyneuropathy (DSPN) is the most common complication of type 2 diabetes mellitus (T2DM) and the most common form of peripheral neuropathy. DSPN increases the risk of foot ulceration up to seven-fold, and is a significant risk factor in more than 60 % of the amputations of the lower limbs in patients with T2DM. The aims of our study were to evaluate the difference in...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2013

ISSN: 0149-5992,1935-5548

DOI: 10.2337/dc13-0176